Tablet Hardness/Disintegration/Friability Testing

Tablet Hardness/Disintegration/Friability Testing
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Tablet hardness
Tablet hardness testing is used to test the breaking point and structural integrity of a tablet prior to storage, transportation, and handling before usage. All Pharma Test tablet hardness testing instruments meet the latest requirements of the USP and EP Pharmacopeia.

Tablet disintegration
Tablet disintegration testing instruments are widely used in the pharmaceutical industry to evaluate the disintegration characteristics of formulations and the quality control of different dosage forms. All Pharma Test tablet and capsule disintegration testers are fully compliant with the current USP and EP Pharmacopeia and support both A-type and B-type baskets for regular or larger samples. They feature a stainless-steel housing, to be more GMP compliant than painted housing designs. Often these instruments are used in QC and IPC laboratories where most of the other equipment uses stainless steel as well. This way the Pharma Test instruments certainly do not look out of place. Pharma Test disintegration testing instruments are available with several levels of automation:

  • Fully automated disintegration testing: PTZ AUTO EZ
  • Semi-automated disintegration testing: PTZ AUTO
  • Manual disintegration testing: PTZ-S, DIST-3

The PT-ODF disintegration basket add-on is a unique device to test the disintegration times of orodispersible films.

Tablet friability
Friability testing is used to test the durability of tablets during packing processes and transit. This involves repeatedly dropping a sample of tablets over a fixed time, using a rotating drum with a baffle. The result is inspected for broken tablets, and the percentage of tablet mass lost through chipping. All Pharma Test friability testers are fully compliant to the current USP, EP and JP Pharmacopeia and come ready to use with friability drums included in the standard scope of supply. Abrasion drums as well as friability drums with anti-static coating are available as options.